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Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases
BACKGROUND: SPOUT methyltransferases (MTases) are a large class of S-adenosyl-L-methionine-dependent enzymes that exhibit an unusual alpha/beta fold with a very deep topological knot. In 2001, when no crystal structures were available for any of these proteins, Anantharaman, Koonin, and Aravind iden...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829167/ https://www.ncbi.nlm.nih.gov/pubmed/17338813 http://dx.doi.org/10.1186/1471-2105-8-73 |