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Detection of subtelomere imbalance using MLPA: validation, development of an analysis protocol, and application in a diagnostic centre
BACKGROUND: Commercial MLPA kits (MRC-Holland) are available for detecting imbalance at the subtelomere regions of chromosomes; each kit consists of one probe for each subtelomere. METHODS: For validation of the kits, 208 patients were tested, of which 128 were known to be abnormal, corresponding to...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831468/ https://www.ncbi.nlm.nih.gov/pubmed/17338807 http://dx.doi.org/10.1186/1471-2350-8-9 |