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Island-wide diversity in single nucleotide polymorphisms of the Plasmodium vivax dihydrofolate reductase and dihydropteroate synthetase genes in Sri Lanka
BACKGROUND: Single nucleotide polymorphisms (SNPs) in the Plasmodium vivax dihydrofolate reductase (Pfdhfr) and dihydropteroate synthetase (Pvdhps) genes cause parasite resistance to the antifolate drug combination, sulphadoxine/pyrimethamine (SP). Monitoring these SNPs provide insights into the lev...
Autores principales: | Schousboe, Mette L, Rajakaruna, Rupika S, Salanti, Ali, Hapuarachchi, Hapuarachchige C, Galappaththy, Gawrie NL, Bygbjerg, Ib C, Amerasinghe, Priyanie H, Konradsen, Flemming, Alifrangis, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831779/ https://www.ncbi.nlm.nih.gov/pubmed/17349045 http://dx.doi.org/10.1186/1475-2875-6-28 |
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