The Role of Presenilin and its Interacting Proteins in the Biogenesis of Alzheimer’s Beta Amyloid

The biogenesis and accumulation of the beta amyloid protein (Aβ) is a key event in the cascade of oxidative and inflammatory processes that characterises Alzheimer’s disease. The presenilins and its interacting proteins play a pivotal role in the generation of Aβ from the amyloid precursor protein (...

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Detalles Bibliográficos
Autores principales: Verdile, Giuseppe, Gandy, Samuel E, Martins, Ralph N.
Formato: Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers-Plenum Publishers 2006
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832151/
https://www.ncbi.nlm.nih.gov/pubmed/16944319
http://dx.doi.org/10.1007/s11064-006-9131-x

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