HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection

BACKGROUND: Statins effectively lower blood cholesterol and the risk of cardiovascular death. Immunomodulatory actions, independent of their lipid-lowering effect, have also been ascribed to these compounds. Since macrophages participate in several vascular pathologies, we examined the effect of sta...

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Detalles Bibliográficos
Autores principales: Vamvakopoulos, Joannis E, Green, Colin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC183828/
https://www.ncbi.nlm.nih.gov/pubmed/12871602
http://dx.doi.org/10.1186/1471-2261-3-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC183828/
https://www.ncbi.nlm.nih.gov/pubmed/12871602
http://dx.doi.org/10.1186/1471-2261-3-6

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