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Clinical implications and utility of field cancerization
Cancer begins with multiple cumulative epigenetic and genetic alterations that sequencially transform a cell, or a group of cells in a particular organ. The early genetic events might lead to clonal expansion of pre-neoplastic daughter cells in a particular tumor field. Subsequent genomic changes in...
Autores principales: | Dakubo, Gabriel D, Jakupciak, John P, Birch-Machin, Mark A, Parr, Ryan L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838897/ https://www.ncbi.nlm.nih.gov/pubmed/17362521 http://dx.doi.org/10.1186/1475-2867-7-2 |
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