Analysis of genetic systems using experimental evolution and whole-genome sequencing

The application of whole-genome sequencing to the study of microbial evolution promises to reveal the complex functional networks of mutations that underlie adaptation. A recent study of parallel evolution in populations of Escherichia coli shows how adaptation involves both functional changes to sp...

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Detalles Bibliográficos
Autores principales: Hegreness, Matthew, Kishony, Roy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839123/
https://www.ncbi.nlm.nih.gov/pubmed/17274841
http://dx.doi.org/10.1186/gb-2007-8-1-201
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author Hegreness, Matthew
Kishony, Roy
author_facet Hegreness, Matthew
Kishony, Roy
author_sort Hegreness, Matthew
collection PubMed
description The application of whole-genome sequencing to the study of microbial evolution promises to reveal the complex functional networks of mutations that underlie adaptation. A recent study of parallel evolution in populations of Escherichia coli shows how adaptation involves both functional changes to specific proteins as well as global changes in regulation.
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spelling pubmed-18391232007-03-30 Analysis of genetic systems using experimental evolution and whole-genome sequencing Hegreness, Matthew Kishony, Roy Genome Biol Minireview The application of whole-genome sequencing to the study of microbial evolution promises to reveal the complex functional networks of mutations that underlie adaptation. A recent study of parallel evolution in populations of Escherichia coli shows how adaptation involves both functional changes to specific proteins as well as global changes in regulation. BioMed Central 2007 2007-02-01 /pmc/articles/PMC1839123/ /pubmed/17274841 http://dx.doi.org/10.1186/gb-2007-8-1-201 Text en Copyright © 2007 BioMed Central Ltd
spellingShingle Minireview
Hegreness, Matthew
Kishony, Roy
Analysis of genetic systems using experimental evolution and whole-genome sequencing
title Analysis of genetic systems using experimental evolution and whole-genome sequencing
title_full Analysis of genetic systems using experimental evolution and whole-genome sequencing
title_fullStr Analysis of genetic systems using experimental evolution and whole-genome sequencing
title_full_unstemmed Analysis of genetic systems using experimental evolution and whole-genome sequencing
title_short Analysis of genetic systems using experimental evolution and whole-genome sequencing
title_sort analysis of genetic systems using experimental evolution and whole-genome sequencing
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839123/
https://www.ncbi.nlm.nih.gov/pubmed/17274841
http://dx.doi.org/10.1186/gb-2007-8-1-201
work_keys_str_mv AT hegrenessmatthew analysisofgeneticsystemsusingexperimentalevolutionandwholegenomesequencing
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