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Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain
BACKGROUND: Cyclooxygenase (COX)-1 and COX-2 produce prostanoids from arachidonic acid and are thought to have important yet distinct roles in normal brain function. Deletion of COX-1 or COX-2 results in profound differences both in brain levels of prostaglandin E(2 )and in activation of the transcr...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839133/ https://www.ncbi.nlm.nih.gov/pubmed/17266762 http://dx.doi.org/10.1186/gb-2007-8-1-r14 |