Adaptation to Human Populations Is Revealed by Within-Host Polymorphisms in HIV-1 and Hepatitis C Virus

CD8(+) cytotoxic T-lymphocytes (CTLs) perform a critical role in the immune control of viral infections, including those caused by human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). As a result, genetic variation at CTL epitopes is strongly influenced by host-specific selection...

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Detalles Bibliográficos
Autores principales: Poon, Art F. Y, Kosakovsky Pond, Sergei L., Bennett, Phil, Richman, Douglas D, Leigh Brown, Andrew J., Frost, Simon D. W
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839164/
https://www.ncbi.nlm.nih.gov/pubmed/17397261
http://dx.doi.org/10.1371/journal.ppat.0030045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839164/
https://www.ncbi.nlm.nih.gov/pubmed/17397261
http://dx.doi.org/10.1371/journal.ppat.0030045

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