Cargando…

Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis

BACKGROUND: Lipids are an important and highly diverse class of molecules having structural, energy storage and signaling roles. Modern analytical technologies afford screening of many lipid molecular species in parallel. One of the biggest challenges of lipidomics is elucidation of important pathob...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yetukuri, Laxman, Katajamaa, Mikko, Medina-Gomez, Gema, Seppänen-Laakso, Tuulikki, Vidal-Puig, Antonio, Orešič, Matej
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839890/ https://www.ncbi.nlm.nih.gov/pubmed/17408502 http://dx.doi.org/10.1186/1752-0509-1-12

Ejemplares similares

Normalization method for metabolomics data using optimal selection of multiple internal standards
por: Sysi-Aho, Marko, et al.
Publicado: (2007)

Human Tear Fluid Lipidome: From Composition to Function
por: Rantamäki, Antti H., et al.
Publicado: (2011)

Association of Lipidome Remodeling in the Adipocyte Membrane with Acquired Obesity in Humans
por: Pietiläinen, Kirsi H., et al.
Publicado: (2011)

Acquired Obesity Is Associated with Changes in the Serum Lipidomic Profile Independent of Genetic Effects – A Monozygotic Twin Study
por: Pietiläinen, Kirsi H., et al.
Publicado: (2007)

PPAR gamma 2 Prevents Lipotoxicity by Controlling Adipose Tissue Expandability and Peripheral Lipid Metabolism
por: Medina-Gomez, Gema, et al.
Publicado: (2007)

Triacylglycerol Fatty Acid Composition in Diet-Induced Weight Loss in Subjects with Abnormal Glucose Metabolism – the GENOBIN Study
por: Schwab, Ursula, et al.
Publicado: (2008)

Fatty Fish Intake Decreases Lipids Related to Inflammation and Insulin Signaling—A Lipidomics Approach
por: Lankinen, Maria, et al.
Publicado: (2009)

Processing methods for differential analysis of LC/MS profile data
por: Katajamaa, Mikko, et al.
Publicado: (2005)

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes
por: Orešič, Matej, et al.
Publicado: (2008)

A Systems Biology Strategy Reveals Biological Pathways and Plasma Biomarker Candidates for Potentially Toxic Statin-Induced Changes in Muscle
por: Laaksonen, Reijo, et al.
Publicado: (2006)

Serum Lipidomics Meets Cardiac Magnetic Resonance Imaging: Profiling of Subjects at Risk of Dilated Cardiomyopathy
por: Sysi-Aho, Marko, et al.
Publicado: (2011)

Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver
por: Kotronen, Anna, et al.
Publicado: (2009)

High Density Lipoprotein Structural Changes and Drug Response in Lipidomic Profiles following the Long-Term Fenofibrate Therapy in the FIELD Substudy
por: Yetukuri, Laxman, et al.
Publicado: (2011)

Gender-dependent progression of systemic metabolic states in early childhood
por: Nikkilä, Janne, et al.
Publicado: (2008)

Phospholipids and insulin resistance in psychosis: a lipidomics study of twin pairs discordant for schizophrenia
por: Orešič, Matej, et al.
Publicado: (2012)

Lipidomic and Metabolomic Signature of Progression of Chronic Kidney Disease in Patients with Severe Obesity
por: Lanzon, Borja, et al.
Publicado: (2021)

Age- and Islet Autoimmunity–Associated Differences in Amino Acid and Lipid Metabolites in Children at Risk for Type 1 Diabetes
por: Pflueger, Maren, et al.
Publicado: (2011)

Decreased Cord-Blood Phospholipids in Young Age–at–Onset Type 1 Diabetes
por: La Torre, Daria, et al.
Publicado: (2013)

Metabolic Regulation in Progression to Autoimmune Diabetes
por: Sysi-Aho, Marko, et al.
Publicado: (2011)

Whole Grain Products, Fish and Bilberries Alter Glucose and Lipid Metabolism in a Randomized, Controlled Trial: The Sysdimet Study
por: Lankinen, Maria, et al.
Publicado: (2011)

Insulin Signaling Regulates Fatty Acid Catabolism at the Level of CoA Activation
por: Xu, Xiaojun, et al.
Publicado: (2012)

Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis
por: Seeßle, Jessica, et al.
Publicado: (2020)

Metabolomic and lipidomic analysis of the effect of pioglitazone on hepatic steatosis in a rat model of obese Type 2 diabetes
por: Yang, Hyekyung, et al.
Publicado: (2018)

Metabolome in schizophrenia and other psychotic disorders: a general population-based study
por: Orešič, Matej, et al.
Publicado: (2011)

Lipidomic Analyses Reveal Modulation of Lipid Metabolism by the PFAS Perfluoroundecanoic Acid (PFUnDA) in Non-Obese Diabetic Mice
por: Hyötyläinen, Tuulia, et al.
Publicado: (2021)

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins
por: Vainio, Paula, et al.
Publicado: (2011)

Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet
por: McCombie, Gregor, et al.
Publicado: (2012)

Hepatic glucose utilization in hepatic steatosis and obesity
por: Keramida, Georgia, et al.
Publicado: (2016)

Differences in Muscle and Adipose Tissue Gene Expression and Cardio-Metabolic Risk Factors in the Members of Physical Activity Discordant Twin Pairs
por: Leskinen, Tuija, et al.
Publicado: (2010)

Metabolite profiling of the carnivorous pitcher plants Darlingtonia and Sarracenia
por: Hotti, Hannu, et al.
Publicado: (2017)

Inheritance of brewing-relevant phenotypes in constructed Saccharomyces cerevisiae × Saccharomyces eubayanus hybrids
por: Krogerus, Kristoffer, et al.
Publicado: (2017)

Dynamics of the Lipidome in a Colon Simulator
por: Kråkström, Matilda, et al.
Publicado: (2023)

Systems medicine and the integration of bioinformatic tools for the diagnosis of Alzheimer's disease
por: Orešič, Matej, et al.
Publicado: (2010)

Euglena gracilis growth and cell composition under different temperature, light and trophic conditions
por: Wang, Yanming, et al.
Publicado: (2018)

Bioconversion to Raspberry Ketone is Achieved by Several Non-related Plant Cell Cultures
por: Häkkinen, Suvi T., et al.
Publicado: (2015)

Proof of Concept for Cell Culture-Based Coffee
por: Aisala, Heikki, et al.
Publicado: (2023)

Obesity and psychotic disorders: uncovering common mechanisms through metabolomics
por: Orešič, Matej
Publicado: (2012)

Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model
por: Martínez-García, Cristina, et al.
Publicado: (2012)

Analysis of Indole Alkaloids from Rhazya stricta Hairy Roots by Ultra-Performance Liquid Chromatography-Mass Spectrometry
por: Akhgari, Amir, et al.
Publicado: (2015)

Integrating post-genomic approaches as a strategy to advance our understanding of health and disease
por: Tang, Jing, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_j6b8fdoit3lt20mc7r9ae3ppnl