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Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools
BACKGROUND: Peptides derived from endogenous antigens can bind to MHC class I molecules. Those which bind with high affinity can invoke a CD8(+ )immune response, resulting in the destruction of infected cells. Much work in immunoinformatics has involved the algorithmic prediction of peptide binding...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847428/ https://www.ncbi.nlm.nih.gov/pubmed/17381846 http://dx.doi.org/10.1186/1745-7580-3-5 |