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A Novel Approach for Determining Cancer Genomic Breakpoints in the Presence of Normal DNA

CDKN2A (encodes p16(INK4A) and p14(ARF)) deletion, which results in both Rb and p53 inactivation, is the most common chromosomal anomaly in human cancers. To precisely map the deletion breakpoints is important to understanding the molecular mechanism of genomic rearrangement and may also be useful f...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Tsueng, Carson, Dennis A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847701/
https://www.ncbi.nlm.nih.gov/pubmed/17440616
http://dx.doi.org/10.1371/journal.pone.0000380

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