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Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells

BACKGROUND: Norrin is a potent Wnt pathway ligand. Aberrant activation of this signaling pathway can result in colon tumors but the role of norrin-based signaling in the genesis of colon cancer, and its relationship to activation of the pathway by traditional Wnt ligands, is not defined. RESULTS: Fr...

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Detalles Bibliográficos
Autores principales: Planutis, Kestutis, Planutiene, Marina, Moyer, Mary Pat, Nguyen, Anthony V, Pérez, Cherlyn A, Holcombe, Randall F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847812/
https://www.ncbi.nlm.nih.gov/pubmed/17386109
http://dx.doi.org/10.1186/1471-2121-8-12