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A Dominant, Recombination-Defective Allele of Dmc1 Causing Male-Specific Sterility
DMC1 is a meiosis-specific homolog of bacterial RecA and eukaryotic RAD51 that can catalyze homologous DNA strand invasion and D-loop formation in vitro. DMC1-deficient mice and yeast are sterile due to defective meiotic recombination and chromosome synapsis. The authors identified a male dominant s...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847842/ https://www.ncbi.nlm.nih.gov/pubmed/17425408 http://dx.doi.org/10.1371/journal.pbio.0050105 |