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Query-Dependent Banding (QDB) for Faster RNA Similarity Searches

When searching sequence databases for RNAs, it is desirable to score both primary sequence and RNA secondary structure similarity. Covariance models (CMs) are probabilistic models well-suited for RNA similarity search applications. However, the computational complexity of CM dynamic programming alig...

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Detalles Bibliográficos
Autores principales: Nawrocki, Eric P, Eddy, Sean R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847999/
https://www.ncbi.nlm.nih.gov/pubmed/17397253
http://dx.doi.org/10.1371/journal.pcbi.0030056

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