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Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage

HIV-1 cell entry commonly uses, in addition to CD4, one of the chemokine receptors CCR5 or CXCR4 as coreceptor. Knowledge of coreceptor usage is critical for monitoring disease progression as well as for supporting therapy with the novel drug class of coreceptor antagonists. Predictive methods for i...

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Detalles Bibliográficos
Autores principales:	Sander, Oliver, Sing, Tobias, Sommer, Ingolf, Low, Andrew J, Cheung, Peter K, Harrigan, P. Richard, Lengauer, Thomas, Domingues, Francisco S
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1848001/ https://www.ncbi.nlm.nih.gov/pubmed/17397254 http://dx.doi.org/10.1371/journal.pcbi.0030058

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