Complete genomic sequences, a key residue in the spike protein and deletions in nonstructural protein 3b of US strains of the virulent and attenuated coronaviruses, transmissible gastroenteritis virus and porcine respiratory coronavirus

Transmissible gastroenteritis virus (TGEV) isolates that have been adapted to passage in cell culture maintain their infectivity in vitro but may lose their pathogenicity in vivo. To better understand the genomic mechanisms for viral attenuation, we sequenced the complete genomes of two virulent TGE...

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Autores principales: Zhang, Xinsheng, Hasoksuz, Mustafa, Spiro, David, Halpin, Rebecca, Wang, Shiliang, Stollar, Sarah, Janies, Daniel, Hadya, Nagesh, Tang, Yuxin, Ghedin, Elodie, Saif, Linda
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850758/
https://www.ncbi.nlm.nih.gov/pubmed/17023013
http://dx.doi.org/10.1016/j.virol.2006.08.051

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