Case-control and family-based association studies of candidate genes in autistic disorder and its endophenotypes: TPH2 and GLO1

BACKGROUND: The TPH2 gene encodes the enzyme responsible for serotonin (5-HT) synthesis in the Central Nervous System (CNS). Stereotypic and repetitive behaviors are influenced by 5-HT, and initial studies report an association of TPH2 alleles with childhood-onset obsessive-compulsive disorder (OCD)...

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Detalles Bibliográficos
Autores principales: Sacco, Roberto, Papaleo, Veruska, Hager, Jorg, Rousseau, Francis, Moessner, Rainald, Militerni, Roberto, Bravaccio, Carmela, Trillo, Simona, Schneider, Cindy, Melmed, Raun, Elia, Maurizio, Curatolo, Paolo, Manzi, Barbara, Pascucci, Tiziana, Puglisi-Allegra, Stefano, Reichelt, Karl-Ludvig, Persico, Antonio M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851007/
https://www.ncbi.nlm.nih.gov/pubmed/17346350
http://dx.doi.org/10.1186/1471-2350-8-11

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