SirT1 modulates the estrogen–insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice

INTRODUCTION: Estrogen and insulin-like growth factor-1 (IGF-1) play important roles in mammary gland development and breast cancer. SirT1 is a highly conserved protein deacetylase that can regulate the insulin/IGF-1 signaling in lower organisms, as well as a growing number of transcription factors,...

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Detalles Bibliográficos
Autores principales: Li, Hongzhe, Rajendran, Grace K, Liu, Ninning, Ware, Carol, Rubin, Brian P, Gu, Yansong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851382/
https://www.ncbi.nlm.nih.gov/pubmed/17201918
http://dx.doi.org/10.1186/bcr1632

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