Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls

INTRODUCTION: Female germline BRCA gene mutation carriers are at increased risk for developing breast cancer. The purpose of our study was to establish whether healthy BRCA mutation carriers demonstrate an increased frequency of aberrant gene promoter hypermethylation in ductal lavage (DL) fluid, co...

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Detalles Bibliográficos
Autores principales: Locke, Imogen, Kote-Jarai, Zsofia, Jo Fackler, Mary, Bancroft, Elizabeth, Osin, Peter, Nerurkar, Ashutosh, Izatt, Louise, Pichert, Gabriella, Gui, Gerald PH, Eeles, Rosalind A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851387/
https://www.ncbi.nlm.nih.gov/pubmed/17324252
http://dx.doi.org/10.1186/bcr1657

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