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Structure-based prediction of C(2)H(2) zinc-finger binding specificity: sensitivity to docking geometry
Predicting the binding specificity of transcription factors is a critical step in the characterization and computational identification and of cis-regulatory elements in genomic sequences. Here we use protein–DNA structures to predict binding specificity and consider the possibility of predicting po...
Autores principales: | Siggers, Trevor W., Honig, Barry |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851644/ https://www.ncbi.nlm.nih.gov/pubmed/17264128 http://dx.doi.org/10.1093/nar/gkl1155 |
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