Systemic administration of IGF-I enhances healing in collagenous extracellular matrices: evaluation of loaded and unloaded ligaments

BACKGROUND: Insulin-like growth factor-I (IGF-I) plays a crucial role in wound healing and tissue repair. We tested the hypotheses that systemic administration of IGF-I, or growth hormone (GH), or both (GH+IGF-I) would improve healing in collagenous connective tissue, such as ligament. These hypothe...

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Detalles Bibliográficos
Autores principales: Provenzano, Paolo P, Alejandro-Osorio, Adriana L, Grorud, Kelley W, Martinez, Daniel A, Vailas, Arthur C, Grindeland, Richard E, Vanderby, Ray
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851714/
https://www.ncbi.nlm.nih.gov/pubmed/17386107
http://dx.doi.org/10.1186/1472-6793-7-2

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