Cargando…

Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens

BACKGROUND: Natural antibodies directed at carbohydrates reject porcine xenografts. They are initially expressed in germline configuration and are encoded by a small number of structurally-related germline progenitors. The transplantation of genetically-modified pig organs prevents hyperacute reject...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kearns-Jonker, Mary, Barteneva, Natasha, Mencel, Robert, Hussain, Namath, Shulkin, Irina, Xu, Alan, Yew, Margaret, Cramer, Donald V
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851715/ https://www.ncbi.nlm.nih.gov/pubmed/17352819 http://dx.doi.org/10.1186/1471-2172-8-3

Ejemplares similares

Cellular basis of the proliferative response of human T cells to mouse xenoantigens
Publicado: (1990)

Sialo-Xenoantigenic Glycobiology: Molecular Glycobiology of Sialylglycan-Xenoantigenic Determinants in Pig to Human Xenotransplantation
por: Song, Kwon-Ho, et al.
Publicado: (2013)

Xenoantigenicity of porcine decellularized valves
por: Helder, Meghana R. K., et al.
Publicado: (2017)

Immunization with a prostate cancer xenoantigen elicits a xenoantigen epitope-specific T-cell response
por: Johnson, Laura E., et al.
Publicado: (2012)

Defining Fibronectin's Cell Adhesion Synergy Site by Site-Directed Mutagenesis
por: Redick, Sambra D., et al.
Publicado: (2000)

Porcine-Stimulated Human Tr1 Cells Showed Enhanced Suppression in Xenoantigen Stimulation Response
por: Chen, Xiaoting, et al.
Publicado: (2021)

CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response
por: Cao, Lu, et al.
Publicado: (2023)

Retracted: Porcine-Stimulated Human Tr1 Cells Showed Enhanced Suppression in Xenoantigen Stimulation Response
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Alpha 1,3-Galactosyltransferase Deficiency in Pigs Increases Sialyltransferase Activities That Potentially Raise Non-Gal Xenoantigenicity
por: Park, Jong-Yi, et al.
Publicado: (2011)

Xenoantigen-Dependent Complement-Mediated Neutralization of Lymphocytic Choriomeningitis Virus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus in Human Serum
por: Pipperger, Lisa, et al.
Publicado: (2019)

Molecular Basis of Inward Rectification: Polyamine Interaction Sites Located by Combined Channel and Ligand Mutagenesis
por: Kurata, Harley T., et al.
Publicado: (2004)

Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc
por: Peri, Sateesh, et al.
Publicado: (2017)

One-Step Generation of Multiple Gene-Edited Pigs by Electroporation of the CRISPR/Cas9 System into Zygotes to Reduce Xenoantigen Biosynthesis
por: Tanihara, Fuminori, et al.
Publicado: (2021)

PFunkel: Efficient, Expansive, User-Defined Mutagenesis
por: Firnberg, Elad, et al.
Publicado: (2012)

Xenoantigen, an αGal epitope-expression construct driven by the hTERT-promoter, specifically kills human pancreatic cancer cell line
por: Sawada, Tokihiko, et al.
Publicado: (2002)

Proceedings: Chemical basis for the relationship between mutagenesis and carcinogenesis.
por: Brookes, P.
Publicado: (1975)

Key Sites for P2X Receptor Function and Multimerization: Overview of Mutagenesis Studies on a Structural Basis
por: Hausmann, Ralf, et al.
Publicado: (2015)

Combined Overlap Extension PCR Method for Improved Site Directed Mutagenesis
por: Hussain, Hasnain, et al.
Publicado: (2016)

Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis
por: Peng, Xi, et al.
Publicado: (2019)

Effect of membrane-bound complement regulatory proteins on tumor cell sensitivity to complement-dependent cytolysis triggered by heterologous expression of the α-gal xenoantigen
por: Wang, Yu, et al.
Publicado: (2018)

Retraction: Cadaveric Study of Anatomic Far Distal Musculocutaneous and Median Nerve Communication
por: Hussain, Namath S
Publicado: (2016)

Routine PSA Testing: An Analysis of the Controversy Concerning Its Use
por: Hussain, Namath S.
Publicado: (2005)

Cadaveric Study of Anatomic Far Distal Musculocutaneous and Median Nerve Communication
por: Hussain, Namath S
Publicado: (2016)

REPLACR-mutagenesis, a one-step method for site-directed mutagenesis by recombineering
por: Trehan, Ashutosh, et al.
Publicado: (2016)

Atomic mutagenesis at the ribosomal decoding site
por: Schrode, Pius, et al.
Publicado: (2016)

Mutagenesis in Rice: The Basis for Breeding a New Super Plant
por: Viana, Vívian Ebeling, et al.
Publicado: (2019)

Analysis of the molecular basis of calmodulin defects that affect ion channel-mediated cellular responses: site-specific mutagenesis and microinjection
Publicado: (1990)

Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.
por: Kao, Y C, et al.
Publicado: (1998)

Adoptive transfer of xenoantigen-stimulated T cell receptor Vβ-restricted human regulatory T cells prevents porcine islet xenograft rejection in humanized mice
por: Jin, Xi, et al.
Publicado: (2018)

Defining a Conformational Consensus Motif in Cotransin-Sensitive Signal Sequences: A Proteomic and Site-Directed Mutagenesis Study
por: Klein, Wolfgang, et al.
Publicado: (2015)

Intravascular Ultrasound for Intracranial and Extracranial Carotid Artery Stent Placement
por: Hussain, Ahmad S, et al.
Publicado: (2016)

A Unique Case of Intracranial Mucormycosis Following an Assault
por: Hussain, Fadilah S, et al.
Publicado: (2016)

Clinical Utility of Thallium-201 Single Photon Emission Computed Tomography and Cerebrospinal Fluid Epstein-Barr Virus Detection Using Polymerase Chain Reaction in the Diagnosis of AIDS-Related Primary Central Nervous System Lymphoma
por: Hussain, Fadilah S, et al.
Publicado: (2016)

Analysis of 1014 consecutive operative cases to determine the utility of intraoperative neurophysiological data
por: Hussain, Namath Syed
Publicado: (2015)

Targeted mutagenesis in Anaplasma marginale to define virulence and vaccine development against bovine anaplasmosis
por: Hove, Paidashe, et al.
Publicado: (2022)

Sorting of small infectious virus particles by flow virometry reveals distinct infectivity profiles
por: Gaudin, Raphaël, et al.
Publicado: (2015)

hERG Gating Microdomains Defined by S6 Mutagenesis and Molecular Modeling
por: Wynia-Smith, Sarah L., et al.
Publicado: (2008)

Saturation mutagenesis defines novel mouse models of severe spine deformity
por: Rios, Jonathan J., et al.
Publicado: (2021)

Function of the ribosomal E-site: a mutagenesis study
por: Sergiev, Petr V., et al.
Publicado: (2005)

Scarless and site-directed mutagenesis in Salmonella enteritidis chromosome
por: Cox, Mandy M, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_k1n36292djurb54u4f6jag5694