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LINE-1 Hypomethylation in Cancer Is Highly Variable and Inversely Correlated with Microsatellite Instability

BACKGROUND: Alterations in DNA methylation in cancer include global hypomethylation and gene-specific hypermethylation. It is not clear whether these two epigenetic errors are mechanistically linked or occur independently. This study was performed to determine the relationship between DNA hypomethyl...

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Detalles Bibliográficos
Autores principales:	Estécio, Marcos R.H., Gharibyan, Vazganush, Shen, Lanlan, Ibrahim, Ashraf E.K., Doshi, Ketan, He, Rong, Jelinek, Jaroslav, Yang, Allen S., Yan, Pearlly S., Huang, Tim H-M., Tajara, Eloiza H., Issa, Jean-Pierre J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851990/ https://www.ncbi.nlm.nih.gov/pubmed/17476321 http://dx.doi.org/10.1371/journal.pone.0000399

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