IMP321 (sLAG-3), an immunopotentiator for T cell responses against a HBsAg antigen in healthy adults: a single blind randomised controlled phase I study

BACKGROUND: LAG-3 (CD223) is a natural high affinity ligand for MHC class II. The soluble form (sLAG-3) induces maturation of monocyte-derived dendritic cells in vitro and is used as a potent Th1-like immune enhancer with many antigens in animal models. To extend this observation to human, a proof o...

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Detalles Bibliográficos
Autores principales: Brignone, Chrystelle, Grygar, Caroline, Marcu, Manon, Perrin, Gaëlle, Triebel, Frédéric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852106/
https://www.ncbi.nlm.nih.gov/pubmed/17394654
http://dx.doi.org/10.1186/1476-8518-5-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852106/
https://www.ncbi.nlm.nih.gov/pubmed/17394654
http://dx.doi.org/10.1186/1476-8518-5-5

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