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IMP321 (sLAG-3), an immunopotentiator for T cell responses against a HBsAg antigen in healthy adults: a single blind randomised controlled phase I study

BACKGROUND: LAG-3 (CD223) is a natural high affinity ligand for MHC class II. The soluble form (sLAG-3) induces maturation of monocyte-derived dendritic cells in vitro and is used as a potent Th1-like immune enhancer with many antigens in animal models. To extend this observation to human, a proof o...

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Detalles Bibliográficos
Autores principales:	Brignone, Chrystelle, Grygar, Caroline, Marcu, Manon, Perrin, Gaëlle, Triebel, Frédéric
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852106/ https://www.ncbi.nlm.nih.gov/pubmed/17394654 http://dx.doi.org/10.1186/1476-8518-5-5

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