In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study

BACKGROUND: Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein, which acts as a chloride channel activated by cyclic AMP (cAMP). The most frequent mutation found in 70% of CF patients is F508del, while premature sto...

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Detalles Bibliográficos
Autores principales: Sermet-Gaudelus, Isabelle, Renouil, Michel, Fajac, Anne, Bidou, Laure, Parbaille, Bastien, Pierrot, Sébastien, Davy, Nolwen, Bismuth, Elise, Reinert, Philippe, Lenoir, Gérard, Lesure, Jean François, Rousset, Jean Pierre, Edelman, Aleksander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852113/
https://www.ncbi.nlm.nih.gov/pubmed/17394637
http://dx.doi.org/10.1186/1741-7015-5-5

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