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Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury
BACKGROUND: The active form of vitamin D (1,25(OH)(2)D(3)) has been shown to inhibit development of inflammatory bowel disease (IBD) in IL-10 KO mice. Here, the role of the vitamin D receptor (VDR) and 1,25(OH)(2)D(3 )in acute experimental IBD was probed. RESULTS: VDR KO mice were extremely sensitiv...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852118/ https://www.ncbi.nlm.nih.gov/pubmed/17397543 http://dx.doi.org/10.1186/1471-2172-8-5 |