Cargando…

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study

BACKGROUND: Variants of uncoupling protein genes UCP1 and UCP2 have been associated with a range of traits. We wished to evaluate contributions of known UCP1 and UCP2 variants to metabolic traits in the Insulin Resistance and Atherosclerosis (IRAS) Family Study. METHODS: We genotyped five promoter o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sale, Michèle M, Hsu, Fang-Chi, Palmer, Nicholette D, Gordon, Candace J, Keene, Keith L, Borgerink, Hermina M, Sharma, Arun J, Bergman, Richard N, Taylor, Kent D, Saad, Mohammed F, Norris, Jill M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852562/ https://www.ncbi.nlm.nih.gov/pubmed/17397545 http://dx.doi.org/10.1186/1472-6823-7-1

Ejemplares similares

Metabolomic profiling of glucose homeostasis in African Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS-FS)
por: Okut, Hayrettin, et al.
Publicado: (2023)

Adiponectin isoform patterns in ethnic-specific ADIPOQ mutation carriers: The IRAS Family Study
por: Tabb, Keri L., et al.
Publicado: (2017)

Adiponectin and the Incidence of Type 2 Diabetes in Hispanics and African Americans: The IRAS Family Study
por: Hanley, Anthony J.G., et al.
Publicado: (2011)

Molecular determinants of inhibition of UCP1-mediated respiratory uncoupling
por: Gagelin, Antoine, et al.
Publicado: (2023)

Relationships between Uncoupling Protein Genes UCP1, UCP2 and UCP3 and Irisin Levels in Residents of the Coldest Region of Siberia
por: Nikanorova, Alena A., et al.
Publicado: (2022)

A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS)
por: Gao, Chuan, et al.
Publicado: (2015)

Insulin Clearance and the Incidence of Type 2 Diabetes in Hispanics and African Americans: The IRAS Family Study
por: Lee, C. Christine, et al.
Publicado: (2013)

Correlation Between Pancreatic Islet Uncoupling Protein-2 (UCP2) mRNA Concentration And Insulin Status in Rats
por: Kassis, Nadim, et al.
Publicado: (2000)

Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases
por: Pravednikova, Anna E., et al.
Publicado: (2020)

A Metabolically Healthy Obese Phenotype in Hispanic Participants in the IRAS Family Study
por: Samaropoulos, Xanthia F., et al.
Publicado: (2013)

Unveiling the Role of the Proton Gateway, Uncoupling Proteins (UCPs), in Cancer Cachexia
por: Joshi, Mit, et al.
Publicado: (2023)

New Aspects of Mitochondrial Uncoupling Proteins (UCPs) and Their Roles in Tumorigenesis
por: Robbins, Delira, et al.
Publicado: (2011)

Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease
por: Huesca-Gómez, Claudia, et al.
Publicado: (2023)

Association of Uncoupling Protein 1 (UCP1) gene polymorphism with obesity: a case-control study
por: Chathoth, Shahanas, et al.
Publicado: (2018)

Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
por: Pettersson-Klein, A.T., et al.
Publicado: (2018)

Overexpression of mitochondrial uncoupling protein 1 (UCP1) induces a hypoxic response in Nicotiana tabacum leaves
por: Barreto, Pedro, et al.
Publicado: (2016)

Uncoupling Protein-1 (UCP1) in the Adult Horse: Correlations with Body Weight, Rectal Temperature and Lipid Profile
por: Arfuso, Francesca, et al.
Publicado: (2021)

Localization of uncoupling protein 1 (UCP-1) in the sebaceous gland of the dorsal region in the Sunda porcupine (Hystrix javanica)
por: PRAWIRA, Andhika Yudha, et al.
Publicado: (2020)

Transcriptome Response Signatures Associated with the Overexpression of a Mitochondrial Uncoupling Protein (AtUCP1) in Tobacco
por: Laitz, Alessandra Vasconcellos Nunes, et al.
Publicado: (2015)

Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes
por: Nyman, Elin, et al.
Publicado: (2017)

Mitochondrial Uncoupling Proteins (UCP1-UCP3) and Adenine Nucleotide Translocase (ANT1) Enhance the Protonophoric Action of 2,4-Dinitrophenol in Mitochondria and Planar Bilayer Membranes
por: Žuna, Kristina, et al.
Publicado: (2021)

The Uncoupling Protein 1 Gene (UCP1) Is Disrupted in the Pig Lineage: A Genetic Explanation for Poor Thermoregulation in Piglets
por: Berg, Frida, et al.
Publicado: (2006)

Evolution of UCP1 Transcriptional Regulatory Elements Across the Mammalian Phylogeny
por: Gaudry, Michael J., et al.
Publicado: (2017)

Meta-Analysis Reveals the Association of Common Variants in the Uncoupling Protein (UCP) 1–3 Genes with Body Mass Index Variability
por: Brondani, Letícia A., et al.
Publicado: (2014)

Ira
por: Petsko, Gregory A
Publicado: (2003)

Genomic characterization of the European sea bass Dicentrarchus labrax reveals the presence of a novel uncoupling protein (UCP) gene family member in the teleost fish lineage
por: Tine, Mbaye, et al.
Publicado: (2012)

Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis
por: Hughes, David A, et al.
Publicado: (2009)

Commentary: Evolution of UCP1 Transcriptional Regulatory Elements Across the Mammalian Phylogeny
por: Fromme, Tobias
Publicado: (2017)

Population Genetic Analysis of the Uncoupling Proteins Supports a Role for UCP3 in Human Cold Resistance
por: Hancock, Angela M., et al.
Publicado: (2011)

Evolutionary history of the UCP gene family: gene duplication and selection
por: Hughes, Joseph, et al.
Publicado: (2008)

Uncoupling protein 1-driven Cre (Ucp1-Cre) is expressed in the epithelial cells of mammary glands and various non-adipose tissues
por: Kim, Kyungchan, et al.
Publicado: (2023)

Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction
por: Ramsden, David B, et al.
Publicado: (2012)

Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with Longevity
por: Rose, Giuseppina, et al.
Publicado: (2011)

Loss of UCP2 Attenuates Mitochondrial Dysfunction without Altering ROS Production and Uncoupling Activity
por: Kukat, Alexandra, et al.
Publicado: (2014)

A Novel High-Throughput Assay for Islet Respiration Reveals Uncoupling of Rodent and Human Islets
por: Wikstrom, Jakob D., et al.
Publicado: (2012)

Five-Year Change in Visceral Adipose Tissue Quantity in a Minority Cohort: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
por: Hairston, Kristen G., et al.
Publicado: (2009)

UCP-3 uncoupling protein confers hypoxia resistance to renal epithelial cells and is upregulated in renal cell carcinoma
por: Braun, Norbert, et al.
Publicado: (2015)

Sequence and Haplotypes Variation of the Ovine Uncoupling Protein-1 Gene (UCP1) and Their Association with Growth and Carcass Traits in New Zealand Romney Lambs
por: An, Qingming, et al.
Publicado: (2018)

Antagonistic effect of TNF-alpha and insulin on uncoupling protein 2 (UCP-2) expression and vascular damage
por: Gómez-Hernández, Almudena, et al.
Publicado: (2014)

In the Early Stages of Diabetes, Rat Retinal Mitochondria Undergo Mild Uncoupling due to UCP2 Activity
por: Osorio-Paz, Ixchel, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_c1qao7glj8jrar43jetg1eqv0e