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Identification of Genes Implicated in Methapyrilene-Induced Hepatotoxicity by Comparing Differential Gene Expression in Target and Nontarget Tissue

BACKGROUND: Toxicogenomics experiments often reveal thousands of transcript alterations that are related to multiple processes, making it difficult to identify key gene changes that are related to the toxicity of interest. OBJECTIVES: The objective of this study was to compare gene expression change...

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Detalles Bibliográficos
Autores principales: Auman, J. Todd, Chou, Jeff, Gerrish, Kevin, Huang, Qihong, Jayadev, Supriya, Blanchard, Kerry, Paules, Richard S.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852695/
https://www.ncbi.nlm.nih.gov/pubmed/17450226
http://dx.doi.org/10.1289/ehp.9396