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Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb
BACKGROUND: Rapamycin is an immunosuppressive which represses translation of transcripts harbouring a polypyrimidine motif downstream of the mRNA cap site through the mammalian target of rapamycin complex. It inhibits the abnormal autologous proliferation of T-cell clones containing a transcriptiona...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852806/ https://www.ncbi.nlm.nih.gov/pubmed/17407584 http://dx.doi.org/10.1186/1742-4690-4-24 |