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Comparative genomics and experimental promoter analysis reveal functional liver-specific elements in mammalian hepatic lipase genes

BACKGROUND: Mammalian hepatic lipase (HL) genes are transcribed almost exclusively in hepatocytes. The basis for this liver-restricted expression is not completely understood. We hypothesized that the responsible cis-acting elements are conserved among mammalian HL genes. To identify these elements,...

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Detalles Bibliográficos
Autores principales: van Deursen, Diederik, Botma, Gert-Jan, Jansen, Hans, Verhoeven, Adrie JM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853088/
https://www.ncbi.nlm.nih.gov/pubmed/17428321
http://dx.doi.org/10.1186/1471-2164-8-99

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