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Comparative genomics and experimental promoter analysis reveal functional liver-specific elements in mammalian hepatic lipase genes
BACKGROUND: Mammalian hepatic lipase (HL) genes are transcribed almost exclusively in hepatocytes. The basis for this liver-restricted expression is not completely understood. We hypothesized that the responsible cis-acting elements are conserved among mammalian HL genes. To identify these elements,...
Autores principales: | van Deursen, Diederik, Botma, Gert-Jan, Jansen, Hans, Verhoeven, Adrie JM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853088/ https://www.ncbi.nlm.nih.gov/pubmed/17428321 http://dx.doi.org/10.1186/1471-2164-8-99 |
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