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The Importance of Bottlenecks in Protein Networks: Correlation with Gene Essentiality and Expression Dynamics
It has been a long-standing goal in systems biology to find relations between the topological properties and functional features of protein networks. However, most of the focus in network studies has been on highly connected proteins (“hubs”). As a complementary notion, it is possible to define bott...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853125/ https://www.ncbi.nlm.nih.gov/pubmed/17447836 http://dx.doi.org/10.1371/journal.pcbi.0030059 |