Intracerebroventricular antisense knockdown of Gα(i2 )results in ciliary stasis and ventricular dilatation in the rat

BACKGROUND: In the CNS, the heterotrimeric G protein Gα(i2 )is a minor Gα subunit with restricted localization in the ventricular regions including the ependymal cilia. The localization of Gα(i2 )is conserved in cilia of different tissues, suggesting a particular role in ciliary function. Although s...

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Detalles Bibliográficos
Autores principales: Mönkkönen, Kati S, Hakumäki, Juhana M, Hirst, Robert A, Miettinen, Riitta A, O'Callaghan, Christopher, Männistö, Pekka T, Laitinen, Jarmo T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855344/
https://www.ncbi.nlm.nih.gov/pubmed/17430589
http://dx.doi.org/10.1186/1471-2202-8-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855344/
https://www.ncbi.nlm.nih.gov/pubmed/17430589
http://dx.doi.org/10.1186/1471-2202-8-26

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