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Intracerebroventricular antisense knockdown of Gα(i2 )results in ciliary stasis and ventricular dilatation in the rat
BACKGROUND: In the CNS, the heterotrimeric G protein Gα(i2 )is a minor Gα subunit with restricted localization in the ventricular regions including the ependymal cilia. The localization of Gα(i2 )is conserved in cilia of different tissues, suggesting a particular role in ciliary function. Although s...
Autores principales: | Mönkkönen, Kati S, Hakumäki, Juhana M, Hirst, Robert A, Miettinen, Riitta A, O'Callaghan, Christopher, Männistö, Pekka T, Laitinen, Jarmo T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855344/ https://www.ncbi.nlm.nih.gov/pubmed/17430589 http://dx.doi.org/10.1186/1471-2202-8-26 |
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