Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report

PURPOSE: To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. METHODS: Observational case report. RESULTS: Stromal edema localized in the graft...

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Autores principales: Kawashima, Motoko, Mochizuki, Hiroshi, Kawakita, Tetsuya, Hatoh, Shin, Shimazaki, Jun, Yamada, Masakazu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855347/
https://www.ncbi.nlm.nih.gov/pubmed/17411422
http://dx.doi.org/10.1186/1752-1947-1-10
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author Kawashima, Motoko
Mochizuki, Hiroshi
Kawakita, Tetsuya
Hatoh, Shin
Shimazaki, Jun
Yamada, Masakazu
author_facet Kawashima, Motoko
Mochizuki, Hiroshi
Kawakita, Tetsuya
Hatoh, Shin
Shimazaki, Jun
Yamada, Masakazu
author_sort Kawashima, Motoko
collection PubMed
description PURPOSE: To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. METHODS: Observational case report. RESULTS: Stromal edema localized in the graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man. After one week of intensive topical corticosteroids, complete reversal of graft edema occurred, with full recovery of visual function. CONCLUSION: The clinical appearance and response to therapy in this case supported the diagnosis of immune-mediated stromal rejection. Ophthalmologists should be aware that stromal rejection may occur in lamellar corneal grafts.
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spelling pubmed-18553472007-04-25 Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report Kawashima, Motoko Mochizuki, Hiroshi Kawakita, Tetsuya Hatoh, Shin Shimazaki, Jun Yamada, Masakazu J Med Case Reports Case Report PURPOSE: To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. METHODS: Observational case report. RESULTS: Stromal edema localized in the graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man. After one week of intensive topical corticosteroids, complete reversal of graft edema occurred, with full recovery of visual function. CONCLUSION: The clinical appearance and response to therapy in this case supported the diagnosis of immune-mediated stromal rejection. Ophthalmologists should be aware that stromal rejection may occur in lamellar corneal grafts. BioMed Central 2007-04-01 /pmc/articles/PMC1855347/ /pubmed/17411422 http://dx.doi.org/10.1186/1752-1947-1-10 Text en Copyright © 2007 Kawashima et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kawashima, Motoko
Mochizuki, Hiroshi
Kawakita, Tetsuya
Hatoh, Shin
Shimazaki, Jun
Yamada, Masakazu
Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report
title Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report
title_full Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report
title_fullStr Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report
title_full_unstemmed Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report
title_short Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report
title_sort presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855347/
https://www.ncbi.nlm.nih.gov/pubmed/17411422
http://dx.doi.org/10.1186/1752-1947-1-10
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