Interplay between Exonic Splicing Enhancers, mRNA Processing, and mRNA Surveillance in the Dystrophic Mdx Mouse

BACKGROUND: Pre-mRNA splicing, the removal of introns from RNA, takes place within the spliceosome, a macromolecular complex composed of five small nuclear RNAs and a large number of associated proteins. Spliceosome assembly is modulated by the 5′ and 3′ splice site consensus sequences situated at t...

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Detalles Bibliográficos
Autores principales: Buvoli, Massimo, Buvoli, Ada, Leinwand, Leslie A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855434/
https://www.ncbi.nlm.nih.gov/pubmed/17487273
http://dx.doi.org/10.1371/journal.pone.0000427

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