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Polymorphism in NEDD4L Is Associated with Increased Salt Sensitivity, Reduced Levels of P-renin and Increased Levels of Nt-proANP

OBJECTIVE: Neuronal precursor cell expressed developmentally down-regulated 4-like (NEDD4L) is a regulator of the amiloride-sensitive epithelial sodium channel (ENaC), thus a candidate gene for salt sensitivity. Carriers of an intact NEDD4L C2-domain, encoded by the NEDD4L rs4149601 (G/A) GG genotyp...

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Detalles Bibliográficos
Autores principales:	Dahlberg, Jonas, Nilsson, Lars-Olof, von Wowern, Fredrik, Melander, Olle
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855992/ https://www.ncbi.nlm.nih.gov/pubmed/17487281 http://dx.doi.org/10.1371/journal.pone.0000432

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