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Identification of a CCR5-Expressing T Cell Subset That Is Resistant to R5-Tropic HIV Infection

Infection with HIV-1 perturbs homeostasis of human T cell subsets, leading to accelerated immunologic deterioration. While studying changes in CD4(+) memory and naïve T cells during HIV-1 infection, we found that a subset of CD4(+) effector memory T cells that are CCR7(−)CD45RO(−)CD45RA(+) (referred...

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Detalles Bibliográficos
Autores principales: Oswald-Richter, Kyra, Grill, Stacy M, Leelawong, Mindy, Tseng, Michelle, Kalams, Spyros A, Hulgan, Todd, Haas, David W, Unutmaz, Derya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1857714/
https://www.ncbi.nlm.nih.gov/pubmed/17465678
http://dx.doi.org/10.1371/journal.ppat.0030058