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Expression profiling of genes regulated by TGF-beta: Differential regulation in normal and tumour cells
BACKGROUND: TGF-beta is one of the key cytokines implicated in various disease processes including cancer. TGF-beta inhibits growth and promotes apoptosis in normal epithelial cells and in contrast, acts as a pro-tumour cytokine by promoting tumour angiogenesis, immune-escape and metastasis. It is n...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858692/ https://www.ncbi.nlm.nih.gov/pubmed/17425807 http://dx.doi.org/10.1186/1471-2164-8-98 |