Cyclin B1–Cdk1 Activation Continues after Centrosome Separation to Control Mitotic Progression

Activation of cyclin B1–cyclin-dependent kinase 1 (Cdk1), triggered by a positive feedback loop at the end of G2, is the key event that initiates mitotic entry. In metaphase, anaphase-promoting complex/cyclosome–dependent destruction of cyclin B1 inactivates Cdk1 again, allowing mitotic exit and cel...

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Detalles Bibliográficos
Autores principales: Lindqvist, Arne, van Zon, Wouter, Karlsson Rosenthal, Christina, Wolthuis, Rob M. F
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858714/
https://www.ncbi.nlm.nih.gov/pubmed/17472438
http://dx.doi.org/10.1371/journal.pbio.0050123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858714/
https://www.ncbi.nlm.nih.gov/pubmed/17472438
http://dx.doi.org/10.1371/journal.pbio.0050123

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