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Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology. Effective treatment of this disorder has been hampered by the lack of availability of agents that selectively target affected joint tissue. We developed a novel pH-sensitive drug delivery system of dexamethasone (Dex) bas...
Autores principales: | Wang, Dong, Miller, Scott C, Liu, Xin-Ming, Anderson, Brian, Wang, Xu Sherry, Goldring, Steven R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860059/ https://www.ncbi.nlm.nih.gov/pubmed/17233911 http://dx.doi.org/10.1186/ar2106 |
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