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Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritis

Inhibition of tumour necrosis factor (TNF)-alpha with biological molecules has proven an effective treatment for rheumatoid arthritis, achieving a 20% improvement in American College of Rheumatology score in up to 65% of patients. The main drawback to these and many other biological treatments has b...

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Detalles Bibliográficos
Autores principales:	Gould, David, Yousaf, Nasim, Fatah, Rewas, Subang, Maria Cristina, Chernajovsky, Yuti
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860065/ https://www.ncbi.nlm.nih.gov/pubmed/17254348 http://dx.doi.org/10.1186/ar2113

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