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Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis
Recent studies have implicated the dying cell as a potential reservoir of modified autoantigens that might initiate and drive systemic autoimmunity in susceptible hosts. A number of subunits of the exosome, a complex of 3'→5' exoribonucleases that functions in a variety of cellular process...
Autores principales: | Schilders, Geurt, Raijmakers, Reinout, Malmegrim, Kelen CR, Walle, Lieselotte Vande, Saelens, Xavier, Vree Egberts, Wilma, van Venrooij, Walther J, Vandenabeele, Peter, Pruijn, Ger JM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860071/ https://www.ncbi.nlm.nih.gov/pubmed/17280603 http://dx.doi.org/10.1186/ar2119 |
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