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Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis
Preclinical osteoarthritis (OA) models are often employed in studies investigating disease-modifying OA drugs (DMOADs). In this study we present a comprehensive, longitudinal evaluation of OA pathogenesis in a rat model of OA, including histologic and biochemical analyses of articular cartilage degr...
Autores principales: | Appleton, C Thomas G, McErlain, David D, Pitelka, Vasek, Schwartz, Neil, Bernier, Suzanne M, Henry, James L, Holdsworth, David W, Beier, Frank |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860072/ https://www.ncbi.nlm.nih.gov/pubmed/17284317 http://dx.doi.org/10.1186/ar2120 |
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