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The availability of the primer activation signal (PAS) affects the efficiency of HIV-1 reverse transcription initiation
Initiation of reverse transcription of a retroviral RNA genome is strictly regulated. The tRNA primer binds to the primer binding site (PBS), and subsequent priming is triggered by the primer activation signal (PAS) that also pairs with the tRNA. We observed that in vitro reverse transcription initi...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865047/ https://www.ncbi.nlm.nih.gov/pubmed/17308346 http://dx.doi.org/10.1093/nar/gkm046 |