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The availability of the primer activation signal (PAS) affects the efficiency of HIV-1 reverse transcription initiation

Initiation of reverse transcription of a retroviral RNA genome is strictly regulated. The tRNA primer binds to the primer binding site (PBS), and subsequent priming is triggered by the primer activation signal (PAS) that also pairs with the tRNA. We observed that in vitro reverse transcription initi...

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Detalles Bibliográficos
Autores principales: Ooms, Marcel, Cupac, Daniel, Abbink, Truus E. M., Huthoff, Hendrik, Berkhout, Ben
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865047/
https://www.ncbi.nlm.nih.gov/pubmed/17308346
http://dx.doi.org/10.1093/nar/gkm046