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Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses
Trichosanthin (TCS) is a type I ribosome-inactivating protein that inactivates ribosome by enzymatically depurinating the A(4324) at the α-sarcin/ricin loop of 28S rRNA. We have shown in this and previous studies that TCS interacts with human acidic ribosomal proteins P0, P1 and P2, which constitute...
Autores principales: | Chan, Denise S.B., Chu, Lai-On, Lee, Ka-Ming, Too, Priscilla H.M., Ma, Kit-Wan, Sze, Kong-Hung, Zhu, Guang, Shaw, Pang-Chui, Wong, Kam-Bo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865052/ https://www.ncbi.nlm.nih.gov/pubmed/17308345 http://dx.doi.org/10.1093/nar/gkm065 |
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