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The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase
There is compelling evidence that proliferating cell nuclear antigen (PCNA), a DNA sliding clamp, co-ordinates the processing and joining of Okazaki fragments during eukaryotic DNA replication. However, a detailed mechanistic understanding of functional PCNA:ligase I interactions has been incomplete...
Autores principales: | Vijayakumar, Sangeetha, Chapados, Brian R., Schmidt, Kristina H., Kolodner, Richard D., Tainer, John A., Tomkinson, Alan E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865074/ https://www.ncbi.nlm.nih.gov/pubmed/17308348 http://dx.doi.org/10.1093/nar/gkm006 |
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