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Conditional Expression of Wnt4 during Chondrogenesis Leads to Dwarfism in Mice
Wnts are expressed in the forming long bones, suggesting roles in skeletogenesis. To examine the action of Wnts in skeleton formation, we developed a genetic system to conditionally express Wnt4 in chondrogenic tissues of the mouse. A mouse Wnt4 cDNA was introduced into the ubiquitously expressed Ro...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865390/ https://www.ncbi.nlm.nih.gov/pubmed/17505543 http://dx.doi.org/10.1371/journal.pone.0000450 |