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Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics

BACKGROUND: α-Conotoxins have exciting therapeutic potential based on their high selectivity and affinity for nicotinic acetylcholine receptors. The spacing between the cysteine residues in α-conotoxins is variable, leading to the classification of sub-families. BuIA is the only α-conotoxin containi...

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Detalles Bibliográficos
Autores principales:	Jin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T, Tan, Chia Chia, Clark, Richard J, Adams, David J, Alewood, Paul F, Craik, David J, Daly, Norelle L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865545/ https://www.ncbi.nlm.nih.gov/pubmed/17445276 http://dx.doi.org/10.1186/1472-6807-7-28

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